High-Containment / Cytotoxic Capabilities
AFC is one of only a few companies in the industry with the knowledge, experience and facilities necessary to handle commercial-scale production of highly potent and cytotoxic compounds.
AFC produced more than nine high-potency active pharmaceutical
ingredients (HPAPIs) at commercial scale for various customers during a
recent three-year period, and more than two metric tons of HPAPIs
Through triple containment, our facilities have safely handled products with an occupational exposure limit (OEL) as low as 0.2 microgram/m3.
The facilities include:
- R&D laboratories designed and dedicated for high-containment chemistry.
- A high-containment quality control (QC) laboratory for sample preparation
- Three dedicated HPAPI production facilities separated from the general production areas.
- One encompasses a simulated moving bed (SMB) production unit with
6x75 mm (3") diameter columns.